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Gingival hyperplasia is an increase in the number of cells and represents exuberant response of the gingival tissue against local and systemic conditions. Some drugs produce changes in oral tissues. Of calcium channel blockers, nifedipine produce gingival enlargement more often. The objective of this study was to report the case of male patient, 57 years old, who attended the dental clinic Unipê complaining of gingival bleeding and no history of diagnosis after visiting a dentist in other institutions. The patient reported having had chronic kidney disease, hypertension, while making use of drugs: furosemide®, ranitina ®, cyclosporine® and captopril®. On examination, there was an increase of the gingival tissue of uneven surface with lobulations involving the middle third of the lower incisors, tooth mobility and bone loss. Once the diagnosis of gingival hyperplasia drug should clarify the patient and the etiology of the disease and treatment options, such as gingiva plasty, warning of the imminent possibility of relapse. As well as guide the patient to seek medical advice for conducting review of medications. It is relevant to the recognition of a systemic change places, and seek through an interview and performed and directed, to observe the cause-effect relationship.
Referências
WRIGHT, JM. Manifestações bucais das reações das drogas. In: Clínicas Odontológicas da América do Norte. Farmacoterapia. Trad. Catach C, Gutemberg C. São Paulo: Roca; 1985. Cap.10, p.149-164.
MARCUCCI, G. Fundamentos de Odontologia Estomatologia. São Paulo: Editora Guanabara Koogan; 2005.
HAREL-RAVIV M, Eckler M, Lalani K, Raviv E, Gornitsky M. Nifedipineinduced gingiva l hyperpl a s i a . A comprehens ive review and analysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod Jun 1995; 79(6) :715-22.
BUTLER, RT; Ka lkwa r f KL , Ka ldahl WB. Drug- induced gingiva l hyperplasia: phenytoin, cyclosporin and nifedipine. J Am Dent Assoc 1987; 144:56-60.
BACKMAN N, Holm AK, Hanstrom L, Blomquist HK, Heijbel J, Safstrom G. Folate treatment of diphenylhydantoin-induced gingival hyperplasia. Scand J Dent Res Jun, 1989; 97(3):222-32.
NEVILLE, B. W. et al. Patologia oral e maxilo facial. Rio de Janeiro : Editora Guanabara Koogan., 2004.
CALNE RY, Thiru S, McMaster P, Cradock GN, White DJG, Evans DB, et al. Cyclosporine A in patients receiving renal allografts from cadaver donors. Lancet 1978; 1:1323-7.
KAHAN BD. Cyclosporine. N Engl J Med 1989; 321: 1725-38.
MARSHALL RI, Bartold MD. A clinical review of drug - induced gingival overgrowth. Aust Dent J 1999; 44:219-32.
MCGAW WT, Lam S, Coates J. Cyclosporine-induced gingival overgrowth: correlation with dental plaque scores, gingivitis scores, and cyclosporine levels in serum and saliva. Oral Surg Oral Med Oral Pathol 1987; 64: 293-7.
KING GN, Fullinfaw R, Higgins TS, Walker RJ, Francis DMA, Wiesenfeld D. Gingival hyperplasia in renal allograft recipients receiving cyclosporine A and calcium antagonists. J Clin Periodontol 1993; 20:286-93.
STEPHEN J Meraw, DDS, Phillip J Sheridan, DDS. Medically induced gingival hyperplasia. Mayo Clin Proc 1998; 73:1196-99
THOMASON JM, Kelly PJ, Seymour RA. The distribution of gingival overgrowth in organ transplant patients. J Clin Periodontol 1996;23:367-71